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Basic information of Tgfb1 :

Official Symbol of Gene Tgfb1
Species Mus musculus
Entrez Gene ID 21803
Official Full Name transforming growth factor, beta 1
Also known as Tgfb; Tgfb-1; TGFbeta1; TGF-beta1
Gene Type protein coding
dbXrefs Ensembl:ENSMUSG00000002603 AllianceGenome:MGI:98725
Map Location 7 A3; 7 13.98 cM

Sample information of multiple sclerosis:

Detected Sample spleen
Sample Detail N/A
Detected Method N/A
Disease EAE
Disease subtype N/A
Population (SWRxSJL/J)F1 mice
Sample Size N/A

Literature information of multiple sclerosis :

Pubmed ID 12828562
Year 2003
Title Chemokine upregulation follows cytokine expression in chronic relapsing experimental autoimmune encephalomyelitis

Results of multiple sclerosis :

Expression up-regulated
Risk type Disease risk
Result Expression of cytokines TNF-b and LT-b preceded, and the expression of TGF-b1 followed chemokine upregulation.
Mechanism/Pathway It was demonstrated in EAE that systemic administration of TGF-b ameliorated the symptoms of the disease.