Basic information of IL33 :
| Official Symbol of Gene | IL33 |
| Species | Homo sapiens |
| Entrez Gene ID | 90865 |
| Official Full Name | interleukin 33 |
| Also known as | DVS27; IL1F11; NF-HEV; NFEHEV; C9orf26 |
| Gene Type | protein coding |
| dbXrefs | Ensembl:ENSG00000137033 MIM:608678; AllianceGenome:HGNC:16028 |
| Map Location | 9p24.1 |
Sample information of multiple sclerosis:
| Detected Sample | blood |
| Sample Detail | N/A |
| Detected Method | ELISA |
| Disease | MS |
| Disease subtype | N/A |
| Population | Iran, Isfahan |
| Sample Size | 140 patients with MS and 72 healthy subjects |
Literature information of multiple sclerosis :
| Pubmed ID | 30950351 |
| Year | 2019 |
| Title | Serum IL-33 Level and IL-33, IL1RL1 Gene Polymorphisms in Asthma and Multiple Sclerosis Patients |
Results of multiple sclerosis :
| Expression | up-regulated |
| Risk type | Disease risk |
| Result | the level of IL33 was significantly higher in patients with asthma (3767.5±1139.8 pg/ml) and MS. |
| Mechanism/Pathway | Thus, increased expression of IL-33 in MS might have an important role in the activation of mast cells that could secrete neurotoxin molecules, increase the permeability of the blood-brain barrier and activate immune cells. |
