Basic information of Elavl1 :
| Official Symbol of Gene | Elavl1 |
| Species | Mus musculus |
| Entrez Gene ID | 15568 |
| Official Full Name | ELAV (embryonic lethal, abnormal vision)-like 1 (Hu antigen R) |
| Also known as | HUR; Hua; 2410055N02Rik |
| Gene Type | protein coding |
| dbXrefs | Ensembl:ENSMUSG00000040028 AllianceGenome:MGI:1100851 |
| Map Location | 8 A1.1; 8 2.0 cM |
Sample information of multiple sclerosis:
| Detected Sample | spinal cord |
| Sample Detail | CD11b+cells |
| Detected Method | Western blot |
| Disease | EAE |
| Disease subtype | N/A |
| Population | CB57BL/6 female mice |
| Sample Size | N/A |
Literature information of multiple sclerosis :
| Pubmed ID | 36696009 |
| Year | 2023 |
| Title | Posttranscriptional Regulation of Gene Expression Participates in the Myelin Restoration in Mouse Models of Multiple Sclerosis: Antisense Modulation of HuR and HuD ELAV RNA Binding Protein |
Results of multiple sclerosis :
| Expression | up-regulation |
| Risk type | Disease risk |
| Result | HuR resulted overexpressed in the spinal cord of MOG35-55–EAE and PLP139-151–EAE mice and was detected in CD11b+cells. |
| Mechanism/Pathway | HuR is an ubiquitous protein that, besides neurons, is expressed in activated microglia |
