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Basic information of Ifng :

Official Symbol of Gene Ifng
Species Mus musculus
Entrez Gene ID 15978
Official Full Name interferon gamma
Also known as Ifg; If2f; IFN-g
Gene Type protein coding
dbXrefs Ensembl:ENSMUSG00000055170 AllianceGenome:MGI:107656
Map Location 10 D2; 10 66.75 cM

Sample information of multiple sclerosis:

Detected Sample N/A
Sample Detail T ceells
Detected Method ELISA
Disease EAE
Disease subtype N/A
Population DR3.DQ6.Aβ° and DQ6.Aβ° mice
Sample Size N/A

Literature information of multiple sclerosis :

Pubmed ID 18490779
Year 2008
Title HLA-DQ6 (DQB1*0601)-restricted T cells protect against experimental autoimmune encephalomyelitis in HLA-DR3.DQ6 double-transgenic mice by generating anti-inflammatory IFN-gamma

Results of multiple sclerosis :

Expression up-regulated
Risk type Disease risk
Result T cells from PLP91–110 peptide-immunized DR3.DQ6.Aβ° and DQ6.Aβ° mice produced high levels of IFN-g compared with DR3.Aβ° mice, while T cells from DR3.Aβ° produced increased levels of IL-6, IL-12, and TNF-γ.
Mechanism/Pathway N/A