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Basic information of Il6 :

Official Symbol of Gene Il6
Species Mus musculus
Entrez Gene ID 3569
Official Full Name interleukin 6
Also known as CDF; HGF; HSF; BSF2; IL-6; BSF-2; IFNB2; IFN-beta-2
Gene Type protein coding
dbXrefs Ensembl:ENSG00000136244 MIM:147620; AllianceGenome:HGNC:6018
Map Location 7p15.3

Sample information of multiple sclerosis:

Detected Sample N/A
Sample Detail T ceells
Detected Method ELISA
Disease EAE
Disease subtype N/A
Population DR3.Aβ° mice
Sample Size N/A

Literature information of multiple sclerosis :

Pubmed ID 18490779
Year 2008
Title HLA-DQ6 (DQB1*0601)-restricted T cells protect against experimental autoimmune encephalomyelitis in HLA-DR3.DQ6 double-transgenic mice by generating anti-inflammatory IFN-gamma

Results of multiple sclerosis :

Expression up-regulated
Risk type Disease risk
Result T cells from PLP91–110 peptide-immunized DR3.DQ6.Aβ° and DQ6.Aβ° mice produced high levels of IFN-g compared with DR3.Aβ° mice, while T cells from DR3.Aβ° produced increased levels of IL-6, IL-12, and TNF-γ.
Mechanism/Pathway N/A