Basic information of Tbx21 :
| Official Symbol of Gene | Tbx21 |
| Species | Mus musculus |
| Entrez Gene ID | 57765 |
| Official Full Name | T-box 21 |
| Also known as | TBT1; Tbet; Tblym |
| Gene Type | protein coding |
| dbXrefs | Ensembl:ENSMUSG00000001444 AllianceGenome:MGI:1888984 |
| Map Location | 11; 11 D |
Sample information of multiple sclerosis:
| Detected Sample | brain |
| Sample Detail | mononuclear cells |
| Detected Method | ELISA |
| Disease | EAE |
| Disease subtype | N/A |
| Population | C57BL/6 mice |
| Sample Size | randomly allocated into four groups (n = 8/group) |
Literature information of multiple sclerosis :
| Pubmed ID | 28946394 |
| Year | 2017 |
| Title | Bifidobacterium animalis in combination with human origin of Lactobacillus plantarum ameliorate neuroinflammation in experimental model of multiple sclerosis by altering CD4+ T cell subset balance |
Results of multiple sclerosis :
| Expression | down-regulation |
| Risk type | Disease risk |
| Result | Noticeably,treatment with combination of L. plantarum and B. animalis strains showed the highest expression level of GATA3and Foxp3mRNA level along with the lowest level of inflammatory tran scription factors, T-bet and ROR-γt, along the all treatment groups and PBS-treated mice. |
| Mechanism/Pathway | N/A |
