Basic information of Il6 :

Official Symbol of Gene	Il6
Species	Mus musculus
Entrez Gene ID	16193
Official Full Name	interleukin 6
Also known as	Il-6
Gene Type	protein coding
dbXrefs	Ensembl:ENSMUSG00000025746 AllianceGenome:MGI:96559
Map Location	5 B1; 5 15.7 cM

Sample information of multiple sclerosis:

Detected Sample	spinal cords
Sample Detail	N/A
Detected Method	ELISA
Disease	EAE
Disease subtype	N/A
Population	SJL/J mice
Sample Size	n=4 per group

Literature information of multiple sclerosis :

Pubmed ID	9637509
Year	1998
Title	The effect of gammadelta T cell depletion on cytokine gene expression in experimental allergic encephalomyelitis

Results of multiple sclerosis :

Expression	down-regulation
Risk type	Disease risk
Result	ELISA data confirmed the reduced levels of IL-1 and IL-6 at disease onset in GL3-treated animals, and pathologic analysis demonstrated a marked reduction in meningeal infiltrates at the same time point.
Mechanism/Pathway	we showed previously that depletion of γδT cells using the mAb GL3 immediately before disease onset, or during the chronic phase, significantly ameliorated clinical severity.