Basic information of IL32 :

Official Symbol of Gene	IL32
Species	Homo sapiens
Entrez Gene ID	9235
Official Full Name	interleukin 32
Also known as	NK4; TAIF; TAIFa; TAIFb; TAIFc; TAIFd; IL-32beta; IL-32alpha; IL-32delta; IL-32gamma
Gene Type	N/A
dbXrefs	Ensembl:ENSG00000008517 MIM:606001; AllianceGenome:HGNC:16830
Map Location	16p13.3

Sample information of multiple sclerosis:

Detected Sample	antecubital vein
Sample Detail	N/A
Detected Method	quantitative sandwich enzyme immunoassay
Disease	MS
Disease subtype	RRMS,PPMS,SPMS
Population	Caucasian origin people
Sample Size	132 MS /172 healthy controls

Literature information of multiple sclerosis :

Pubmed ID	28716229
Year	2017
Title	Association between interleukin-32 polymorphism and multiple sclerosis

Results of multiple sclerosis :

Expression	up-regulation
Risk type	Disease risk
Result	Serum levels of IL-32 were significantly different between MS patients and controls. IL-32 was dramatically higher in the patients than that healthy controls.
Mechanism/Pathway	IL-32, a pluripotent proinflammatory cytokine, may have a role in intensifying the inflammation. It has the double effects on inflammation through augmentation of secretion various inflammatory cytokines as well as enhancing cells migration to the site of inflammation.