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Basic information of Nmnat2 :

Official Symbol of Gene Nmnat2
Species Mus musculus
Entrez Gene ID 226518
Official Full Name nicotinamide nucleotide adenylyltransferase 2
Also known as PNAT1; PNAT2; D030041I09Rik
Gene Type protein coding
dbXrefs Ensembl:ENSMUSG00000042751 AllianceGenome:MGI:2444155
Map Location 1; 1 G3
Variation Type overexpression
refSNP ID N/A

Sample information of multiple sclerosis:

Detected Sample brain
Sample Detail N/A
Detected Method real-time PCR
Disease EAE
Disease subtype N/A
Population C57BL/6J mice
Sample Size N/A

Literature information of multiple sclerosis :

Pubmed ID 34707482
Year 2021
Title Neuronal NMNAT2 Overexpression Does Not Achieve Significant Neuroprotection in Experimental Autoimmune Encephalomyelitis/Optic Neuritis

Results of multiple sclerosis :

Risk Type Disease risk
Main Result Negative
Result NMNAT2 activation in RGCs does not provide significant neuroprotection of RGCs in EAE/optic neuritis.
Mechanism/Pathway N/A