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Basic information of TRA :

Official Symbol of Gene TRA
Species Homo sapiens
Entrez Gene ID 6955
Official Full Name T cell receptor alpha locus
Also known as IMD7; TCRA; TRA@
Gene Type protein coding
dbXrefs AllianceGenome:HGNC:12027
Map Location 14q11.2
Variation Type polymorphism
refSNP ID TCRAC1

Sample information of multiple sclerosis:

Detected Sample N/A
Sample Detail DNA samples
Detected Method PCR
Disease MS
Disease subtype RRMS,CPMS
Population Belgium,Euro-Caucasian
Sample Size 71 unrelated Belgian patients,Sixty-seven randomly selected healthy individuals

Literature information of multiple sclerosis :

Pubmed ID 7911477
Year 1994
Title HLA and T-cell receptor polymorphisms in Belgian multiple sclerosis patients: no evidence for disease association with the T-cell receptor

Results of multiple sclerosis :

Risk Type disease risk
Main Result Negative
Result Although the HLA DR2 genotype was significantly associated with MS, no interactive effects were seen with MS, DR2, TCRAC1, TCRBC2 and TCRBV alleles.
Mechanism/Pathway N/A