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Basic information of FasL :

Official Symbol of Gene FasL
Species Homo sapiens
Entrez Gene ID 356
Official Full Name Fas ligand
Also known as APTL; FASL; CD178; CD95L; ALPS1B; CD95-L; TNFSF6; TNLG1A; APT1LG1
Gene Type protein coding
dbXrefs Ensembl:ENSG00000117560 MIM:134638; AllianceGenome:HGNC:11936
Map Location 1q24.3
Variation Type allel
refSNP ID B

Sample information of multiple sclerosis:

Detected Sample blood
Sample Detail peripheral blood cells
Detected Method PCR-SSP
Disease MS
Disease subtype N/A
Population Spanish and American populations
Sample Size 139 healthy controls and a cohort of 177 unrelated relapsing and remitting multiple sclerosis MS patient

Literature information of multiple sclerosis :

Pubmed ID 11438180
Year 2001
Title Association of a CA repeat polymorphism upstream of the Fas ligand gene with multiple sclerosis

Results of multiple sclerosis :

Risk Type Disease risk
Main Result Positive
Result The HLA DRB1 1501–DQB1 0602 haplotype is associated with B allele with a relative frequency higher than A allele 0.52 and 0.48 in patients vs. 0.68 and 0.32 in controls .
Mechanism/Pathway N/A