Basic information of IGH :
| Official Symbol of Gene | IGH |
| Species | Homo sapiens |
| Entrez Gene ID | 3492 |
| Official Full Name | immunoglobulin heavy locus |
| Also known as | IGD1; IGH@; IGHJ; IGHV; IGHD@; IGHJ@; IGHV@; IGH.1@; IGHDY1 |
| Gene Type | protein coding |
| dbXrefs | MIM:146910; MIM:147010; MIM:147070; AllianceGenome:HGNC:5477 |
| Map Location | 14q32.33 |
| Variation Type | SNP |
| refSNP ID | rs11621145 |
Sample information of multiple sclerosis:
| Detected Sample | cerebrospinal fluid |
| Sample Detail | N/A |
| Detected Method | N/A |
| Disease | MS |
| Disease subtype | N/A |
| Population | Spanish and UK cohorts |
| Sample Size | 2726 patients with MS and 2133 healthy controls |
Literature information of multiple sclerosis :
| Pubmed ID | 25392328 |
| Year | 2015 |
| Title | A new risk variant for multiple sclerosis at the immunoglobulin heavy chain locus associates with intrathecal IgG, IgM index and oligoclonal bands |
Results of multiple sclerosis :
| Risk Type | Disease risk |
| Main Result | Positive |
| Result | We found that rs11621145 showed statistically significant evidence for association with susceptibility to MS. |
| Mechanism/Pathway | N/A |
