Basic information of TNF :
| Official Symbol of Gene | TNF |
| Species | Homo sapiens |
| Entrez Gene ID | 7124 |
| Official Full Name | tumor necrosis factor |
| Also known as | DIF; TNFA; TNFSF2; TNLG1F; TNF-alpha |
| Gene Type | protein coding |
| dbXrefs | Ensembl:ENSG00000232810 MIM:191160; AllianceGenome:HGNC:11892 |
| Map Location | 6p21.33 |
| Variation Type | polymorphisms |
| refSNP ID | (-238) |
Sample information of multiple sclerosis:
| Detected Sample | peripheral venous blood |
| Sample Detail | mononuclear cells |
| Detected Method | PCR-RFLP |
| Disease | MS |
| Disease subtype | N/A |
| Population | Turkish |
| Sample Size | 86 caucasion Turkish MS patients,one hundred and fifty ethnically matched healthy unrelated individuals |
Literature information of multiple sclerosis :
| Pubmed ID | 20082645 |
| Year | 2010 |
| Title | TNF-alpha promoter polymorphisms in multiple sclerosis: no association with -308 and -238 alleles, but the -857 alleles in associated with the disease in Turkish patients |
Results of multiple sclerosis :
| Risk Type | Disease risk |
| Main Result | Negative |
| Result | No differences in the distribution of the TNF-a )238 and )308 alleles were observed. |
| Mechanism/Pathway | N/A |
