Basic information of PTPRC :

Official Symbol of Gene	PTPRC
Species	Homo sapiens
Entrez Gene ID	5788
Official Full Name	protein tyrosine phosphatase receptor type C
Also known as	LCA; LY5; B220; CD45; L-CA; T200; CD45R; GP180; IMD105
Gene Type	protein coding
dbXrefs	Ensembl:ENSG00000081237 MIM:151460; AllianceGenome:HGNC:9666
Map Location	1q31.3-q32.1
Variation Type	mutation
refSNP ID	C->G mutation in position 77 of exon 4

Sample information of multiple sclerosis:

Detected Sample	N/A
Sample Detail	N/A
Detected Method	PCR
Disease	MS
Disease subtype	N/A
Population	Italian
Sample Size	MS patients (n=194),Healthy donors (n=222)

Literature information of multiple sclerosis :

Pubmed ID	12147336
Year	2002
Title	Protein tyrosine phosphatase receptor-type C exon 4 gene mutation distribution in an Italian multiple sclerosis population

Results of multiple sclerosis :

Risk Type	Disease risk
Main Result	Positive
Result	This finding suggests a role, in at least a group of patients, for the PTPRC mutation in genetic susceptibility to MS.
Mechanism/Pathway	N/A