Basic information of TRB :
| Official Symbol of Gene | TRB |
| Species | Homo sapiens |
| Entrez Gene ID | 6957 |
| Official Full Name | T cell receptor beta locu |
| Also known as | TCRB; TRB@ |
| Gene Type | protein coding |
| dbXrefs | AllianceGenome:HGNC:12155 |
| Map Location | 7q34 |
| Variation Type | rearrangement |
| refSNP ID | N/A |
Sample information of multiple sclerosis:
| Detected Sample | peripheral blood |
| Sample Detail | CD4+ human T-cell |
| Detected Method | Southern blot |
| Disease | MS |
| Disease subtype | N/A |
| Population | N/A |
| Sample Size | A mS patient |
Literature information of multiple sclerosis :
| Pubmed ID | 1710434 |
| Year | 1991 |
| Title | Heterogeneity of the T-cell receptor beta gene rearrangements generated in myelin basic protein-specific T-cell clones isolated from a patient with multiple sclerosis |
Results of multiple sclerosis :
| Risk Type | Disease risk |
| Main Result | Positive |
| Result | Thus, the human T-cell response to myelin basic protein is exceedingly heterogeneous, even among T cells that recognize the same small fragment of the molecule in association with the same class I1 restriction element. |
| Mechanism/Pathway | N/A |
