Basic information of SPON1 :
| Official Symbol of Gene | SPON1 |
| Species | Homo sapiens |
| Entrez Gene ID | 10418 |
| Official Full Name | spondin 1 |
| Also known as | f-spondin; VSGP/F-spondin |
| Gene Type | protein coding |
| dbXrefs | Ensembl:ENSG00000262655 MIM:604989; AllianceGenome:HGNC:11252 |
| Map Location | 11p15.2 |
| Variation Type | SNP |
| refSNP ID | rs7104613T |
Sample information of multiple sclerosis:
| Detected Sample | blood |
| Sample Detail | N/A |
| Detected Method | N/A |
| Disease | MS |
| Disease subtype | PMS |
| Population | N/A |
| Sample Size | Ninety-nine PMS and 214 RRMS patients |
Literature information of multiple sclerosis :
| Pubmed ID | 33864731 |
| Year | 2021 |
| Title | Assessment of the genetic contribution to brain magnetic resonance imaging lesion load and atrophy measures in multiple sclerosis patients |
Results of multiple sclerosis :
| Risk Type | Phenotypic risk |
| Main Result | Positive |
| Result | Specifically, in PMS we found evidence of association for the rs7104613 T in gene SPON1, which was associated with a reduction of DeepGMV and was the only marker withstanding multiple testing correction according to our estimated number of effective tests. |
| Mechanism/Pathway | N/A |
