Basic information of MBP :
| Official Symbol of Gene | MBP |
| Species | Homo sapiens |
| Entrez Gene ID | 4155 |
| Official Full Name | myelin basic protein |
| Also known as | N/A |
| Gene Type | protein coding |
| dbXrefs | Ensembl:ENSG00000197971 MIM:159430; AllianceGenome:HGNC:6925 |
| Map Location | 18q23 |
| Variation Type | allel |
| refSNP ID | B |
Sample information of multiple sclerosis:
| Detected Sample | peripheral blood |
| Sample Detail | N/A |
| Detected Method | PCR |
| Disease | MS |
| Disease subtype | RRMS,SPMS,PPMS |
| Population | Italians and Russians |
| Sample Size | Two hundred sixty-nine unrelated patients with definite MS and 385 unrelated healthy control subjects |
Literature information of multiple sclerosis :
| Pubmed ID | 12939427 |
| Year | 2003 |
| Title | Myelin basic protein gene is associated with MS in DR4- and DR5-positive Italians and Russians |
Results of multiple sclerosis :
| Risk Type | Disease risk |
| Main Result | Positive |
| Result | When MS patients and healthy control subjects were stratified according to HLA-DRB1 phenotypes, a significant association of MS with MBP alleles was found only in the DR4- and DR5-positive subgroups. |
| Mechanism/Pathway | N/A |
