Basic information of IL1RN :
| Official Symbol of Gene | IL1RN |
| Species | Homo sapiens |
| Entrez Gene ID | 3557 |
| Official Full Name | interleukin 1 receptor antagonist |
| Also known as | DIRA; IRAP; IL1F3; IL1RA; MVCD4; IL-1RN; IL-1ra; IL-1ra3; ICIL-1RA |
| Gene Type | protein coding |
| dbXrefs | Ensembl:ENSG00000136689 MIM:147679; AllianceGenome:HGNC:6000 |
| Map Location | 2q14.1 |
| Variation Type | polymorphisms |
| refSNP ID | A1/A2 |
Sample information of multiple sclerosis:
| Detected Sample | blood |
| Sample Detail | mononuclear cells |
| Detected Method | PCR |
| Disease | MS |
| Disease subtype | N/A |
| Population | Italian |
| Sample Size | 339 Italian MS patients and 339 healthy controls |
Literature information of multiple sclerosis :
| Pubmed ID | 10371542 |
| Year | 1999 |
| Title | Relevance of interleukin 1 receptor antagonist intron 2 polymorphism in Italian MS patients |
Results of multiple sclerosis :
| Risk Type | Phenotypic risk |
| Main Result | Positive |
| Result | A more aggressive disease course was also associated with A11 genotypes and might reflect the reduced ability of mononuclear cell cultures of A11 HCs to produce IL-1Ra. |
| Mechanism/Pathway | N/A |
