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Basic information of IL1RN :

Official Symbol of Gene IL1RN
Species Homo sapiens
Entrez Gene ID 3557
Official Full Name interleukin 1 receptor antagonist
Also known as DIRA; IRAP; IL1F3; IL1RA; MVCD4; IL-1RN; IL-1ra; IL-1ra3; ICIL-1RA
Gene Type protein coding
dbXrefs Ensembl:ENSG00000136689 MIM:147679; AllianceGenome:HGNC:6000
Map Location 2q14.1
Variation Type polymorphisms
refSNP ID A2/A2

Sample information of multiple sclerosis:

Detected Sample blood
Sample Detail mononuclear cells
Detected Method PCR
Disease MS
Disease subtype N/A
Population Italian
Sample Size 339 Italian MS patients and 339 healthy controls

Literature information of multiple sclerosis :

Pubmed ID 10371542
Year 1999
Title Relevance of interleukin 1 receptor antagonist intron 2 polymorphism in Italian MS patients

Results of multiple sclerosis :

Risk Type Phenotypic risk
Main Result Positive
Result The A1/A1 genotype was more (and the A2/A2 less) represented among MS patients than it was in HCs.
Mechanism/Pathway N/A