Basic information of HLA-DRB1 :
| Official Symbol of Gene | HLA-DRB1 |
| Species | Homo sapiens |
| Entrez Gene ID | 3123 |
| Official Full Name | major histocompatibility complex, class II, DR beta 1 |
| Also known as | SS1; DRB1; HLA-DRB; HLA-DR1B |
| Gene Type | protein coding |
| dbXrefs | Ensembl:ENSG00000196126 MIM:142857; AllianceGenome:HGNC:4948 |
| Map Location | 6p21.32 |
| Variation Type | polymorphisms |
| refSNP ID | DRB1*010 |
Sample information of multiple sclerosis:
| Detected Sample | blood |
| Sample Detail | peripheral blood cells |
| Detected Method | PCR-SSP |
| Disease | MS |
| Disease subtype | RRMS |
| Population | White and Mulatto samples from Brazil |
| Sample Size | 113 consecutive patients (84 White and 29 Mulatto individuals) and 114 blood donors(86 White and 28 Mulatto individuals) |
Literature information of multiple sclerosis :
| Pubmed ID | 17681614 |
| Year | 2007 |
| Title | Association of the HLA-DRB1*15 allele group and the DRB1*1501 and DRB1*1503 alleles with multiple sclerosis in White and Mulatto samples from Brazil |
Results of multiple sclerosis :
| Risk Type | Disease risk |
| Main Result | Negative |
| Result | HLA-DRB1 allele frequencies in the Mulatto sample of patients showing relapsing/remitting multiple sclerosis (MS) and healthy Mulatto controls |
| Mechanism/Pathway | N/A |
