Basic information of TRA :
| Official Symbol of Gene | TRA |
| Species | Homo sapiens |
| Entrez Gene ID | 6955 |
| Official Full Name | T cell receptor alpha locus |
| Also known as | IMD7; TCRA; TRA@ |
| Gene Type | protein coding |
| dbXrefs | AllianceGenome:HGNC:12027 |
| Map Location | 14q11.2 |
| Variation Type | polymorphism |
| refSNP ID | Va6 |
Sample information of multiple sclerosis:
| Detected Sample | N/A |
| Sample Detail | ripheral blood |
| Detected Method | PCR |
| Disease | MS |
| Disease subtype | N/A |
| Population | N/A |
| Sample Size | (familial MS; n = 47)(sporadic MS; n = 47);(1) 37 unaffected siblings of familial MS patients; (2) 60 parents of familial MS patients (alleles not inherited by their affected child); (3) 29 insulin-dependent diabetes mellitus (IDDM) patients seen at the London, Ontario Diabetes Clinic; and (4) 97 unrelated healthy Caucasians of Northern European de scent presently living in London, Ontario. |
Literature information of multiple sclerosis :
| Pubmed ID | 1387654 |
| Year | 1992 |
| Title | T cell receptor alpha chain polymorphisms in multiple sclerosis |
Results of multiple sclerosis :
| Risk Type | disease risk |
| Main Result | Negative |
| Result | Among 30 informa tive families, there was no significant increase in haplotypes shared by affected siblings over that expected based on random segregation. |
| Mechanism/Pathway | N/A |
