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Basic information of PON1 :

Official Symbol of Gene PON1
Species Homo sapiens
Entrez Gene ID 5444
Official Full Name paraoxonase 1
Also known as ESA; PON; MVCD5
Gene Type protein coding
dbXrefs Ensembl:ENSG00000005421 MIM:168820; AllianceGenome:HGNC:9204
Map Location 7q21.3
Variation Type polymorphisms
refSNP ID (M55L)

Sample information of multiple sclerosis:

Detected Sample N/A
Sample Detail N/A
Detected Method N/A
Disease MS
Disease subtype N/A
Population Kazakhs, Russians, and offsprings from mixed marriages
Sample Size N/A

Literature information of multiple sclerosis :

Pubmed ID 21866867
Year 2011
Title [Polymorphic markers of some genes associated with multiple sclerosis in the population of Kazakhstan]

Results of multiple sclerosis :

Risk Type Disease risk
Main Result Negative
Result No significant differences were revealed in the distribution of the genotypes and in the frequencies of alleles at the polymorphic sites of the genes IL-1beta (-511 C/T), IL-2 (-475 A/T and -631 G/A), PON1 (M55L), and UCP2 (-866 G/A).
Mechanism/Pathway N/A