Basic information of TNF :
| Official Symbol of Gene | TNF |
| Species | Homo sapiens |
| Entrez Gene ID | 7124 |
| Official Full Name | tumor necrosis factor |
| Also known as | DIF; TNFA; TNFSF2; TNLG1F; TNF-alpha |
| Gene Type | protein coding |
| dbXrefs | Ensembl:ENSG00000232810 MIM:191160; AllianceGenome:HGNC:11892 |
| Map Location | 6p21.33 |
| Variation Type | polymorphisms |
| refSNP ID | (-308 A/G) |
Sample information of multiple sclerosis:
| Detected Sample | N/A |
| Sample Detail | N/A |
| Detected Method | N/A |
| Disease | MS |
| Disease subtype | N/A |
| Population | Russian |
| Sample Size | N/A |
Literature information of multiple sclerosis :
| Pubmed ID | 21866867 |
| Year | 2011 |
| Title | [Polymorphic markers of some genes associated with multiple sclerosis in the population of Kazakhstan] |
Results of multiple sclerosis :
| Risk Type | Disease risk |
| Main Result | Positive |
| Result | Statistically significant (p < 0.05) differences between the MS patients and healthy individuals were observed in the distribution of the genotypes at site -634 G/C of the IL-6 gene in the Kazakh group, in the allelic frequencies at site -308 A/G in the promoter region of the TNFalpha gene in the Russian group, and in the frequencies of alleles at the polymorphic Q 192R locus of the PON1 gene in the Kazakh group. |
| Mechanism/Pathway | N/A |
