Basic information of LRP2 :
| Official Symbol of Gene | LRP2 |
| Species | Homo sapiens |
| Entrez Gene ID | 4036 |
| Official Full Name | LDL receptor related protein 2 |
| Also known as | DBS; GP330; LRP-2 |
| Gene Type | protein coding |
| dbXrefs | Ensembl:ENSG00000081479 MIM:600073; AllianceGenome:HGNC:6694 |
| Map Location | 2q31.1 |
| Variation Type | allel |
| refSNP ID | rs12988804*T |
Sample information of multiple sclerosis:
| Detected Sample | N/A |
| Sample Detail | N/A |
| Detected Method | N/A |
| Disease | MS |
| Disease subtype | N/A |
| Population | Belgian |
| Sample Size | 527 Belgian |
Literature information of multiple sclerosis :
| Pubmed ID | 29303040 |
| Year | 2018 |
| Title | Genetic basis for relapse rate in multiple sclerosis: Association with LRP2 genetic variation |
Results of multiple sclerosis :
| Risk Type | Phenotypic risk |
| Main Result | Positive |
| Result | The rs12988804*T allele is associated with a 1.16-fold increased hazard rate for a relapse occurring (P = 0.0078) and a higher baseline relapse rate prior to immunomodulatory treatment (P = 0.044). |
| Mechanism/Pathway | N/A |
