Basic information of HLA-DRB1 :
| Official Symbol of Gene | HLA-DRB1 |
| Species | Homo sapiens |
| Entrez Gene ID | 3123 |
| Official Full Name | major histocompatibility complex, class II, DR beta 1 |
| Also known as | SS1; DRB1; HLA-DRB; HLA-DR1B |
| Gene Type | protein coding |
| dbXrefs | Ensembl:ENSG00000196126 MIM:142857; AllianceGenome:HGNC:4948 |
| Map Location | 6p21.32 |
| Variation Type | polymorphisms |
| refSNP ID | DRB1*15 |
Sample information of multiple sclerosis:
| Detected Sample | peripheral blood |
| Sample Detail | N/A |
| Detected Method | PCR-SSP and/or Luminex (PCR-SSO) |
| Disease | MS |
| Disease subtype | N/A |
| Population | Moroccan population |
| Sample Size | Fifty-seven MS patients were compared to 172 healthy controls |
Literature information of multiple sclerosis :
| Pubmed ID | 23849771 |
| Year | 2013 |
| Title | Genetic factors and multiple sclerosis in the Moroccan population: a role for HLA class II |
Results of multiple sclerosis :
| Risk Type | Disease risk |
| Main Result | Positive |
| Result | A significant increase of DRB1*15 allele frequency and HLA-DRB1*15-DQB1*06 haplotype were observed in Moroccan MS patients. |
| Mechanism/Pathway | N/A |
