Basic information of SIM1 :
| Official Symbol of Gene | SIM1 |
| Species | Homo sapiens |
| Entrez Gene ID | 6492 |
| Official Full Name | SIM bHLH transcription factor 1 |
| Also known as | bHLHe14 |
| Gene Type | protein coding |
| dbXrefs | Ensembl:ENSG00000112246 MIM:603128; AllianceGenome:HGNC:10882 |
| Map Location | 6q16.3 |
| Variation Type | SNP |
| refSNP ID | rs924974 |
Sample information of multiple sclerosis:
| Detected Sample | N/A |
| Sample Detail | N/A |
| Detected Method | N/A |
| Disease | MS |
| Disease subtype | N/A |
| Population | Nuoro Province, Sardinia, Italy |
| Sample Size | 15 multiplex families and 94 unrelated controls |
Literature information of multiple sclerosis :
| Pubmed ID | 28933650 |
| Year | 2018 |
| Title | Investigating multiple sclerosis genetic susceptibility on the founder population of east-central Sardinia via association and linkage analysis of immune-related loci |
Results of multiple sclerosis :
| Risk Type | disease risk |
| Main Result | Positive |
| Result | We identified nine best non-MHC independent SNPs (r2<0.70 within a windows size of 100Kb), which were not previously identified by IMSGC and hence represent novel suggestive MS variants. |
| Mechanism/Pathway | N/A |
