Basic information of LTA :
| Official Symbol of Gene | LTA |
| Species | Homo sapiens |
| Entrez Gene ID | 4049 |
| Official Full Name | lymphotoxin alpha |
| Also known as | LT; TNFB; TNFSF1; TNLG1E |
| Gene Type | protein coding |
| dbXrefs | Ensembl:ENSG00000226979 MIM:153440; AllianceGenome:HGNC:6709 |
| Map Location | 6p21.33 |
| Variation Type | polymorphisms |
| refSNP ID | TNF-b*2/*2 |
Sample information of multiple sclerosis:
| Detected Sample | blood |
| Sample Detail | N/A |
| Detected Method | PCR |
| Disease | MS |
| Disease subtype | N/A |
| Population | Belgian |
| Sample Size | 51 unrelated Belgian patients |
Literature information of multiple sclerosis :
| Pubmed ID | 9098447 |
| Year | 1994 |
| Title | Polymorphism of the tumour necrosis factor beta gene in multiple sclerosis and rheumatoid arthritis |
Results of multiple sclerosis :
| Risk Type | Disease risk |
| Main Result | Negative |
| Result | However, the co-occurrence of HLA-DRB 1 * 15,16 and the TNF-b*2 allele gives rise to a slightly increased relative risk for MS(RR =5.39). No such increase was found for the DRB 1 *04 positive RA patients. |
| Mechanism/Pathway | N/A |
