Basic information of HLA-DRB5 :
| Official Symbol of Gene | HLA-DRB5 |
| Species | Homo sapiens |
| Entrez Gene ID | 3127 |
| Official Full Name | major histocompatibility complex, class II, DR beta 5 |
| Also known as | DRB5; HLA-DRB5* |
| Gene Type | protein coding |
| dbXrefs | Ensembl:ENSG00000198502 MIM:604776; AllianceGenome:HGNC:4953 |
| Map Location | 6p21.32 |
| Variation Type | polymorphisms |
| refSNP ID | DRB5*0101 |
Sample information of multiple sclerosis:
| Detected Sample | blood |
| Sample Detail | peripheral blood lymphocytes |
| Detected Method | PCR |
| Disease | MS |
| Disease subtype | N/A |
| Population | Hong Kong |
| Sample Size | eleven Hong Kong MS patients and 36 healthy controls |
Literature information of multiple sclerosis :
| Pubmed ID | 1567812 |
| Year | 1992 |
| Title | Novel HLA-DR2-related haplotypes in Hong Kong Chinese implicate the DQB1*0602 allele in susceptibility to multiple sclerosis |
Results of multiple sclerosis :
| Risk Type | Disease risk |
| Main Result | Negative |
| Result | Novel DR,DQ linkage disequilibrium relationship in Hong Kong Chinese have permitted recognition of DQB1*0602 as a susceptibility allele in DRZpositive MS patients, although a role for the DRBl*1501 allele in MS pathogenesis has not been excluded by this study. |
| Mechanism/Pathway | N/A |
