Basic information of HLA-DQB1 :
| Official Symbol of Gene | HLA-DQB1 |
| Species | Homo sapiens |
| Entrez Gene ID | 3119 |
| Official Full Name | major histocompatibility complex, class II, DQ beta 1 |
| Also known as | IDDM1; CELIAC1; HLA-DQB |
| Gene Type | protein coding |
| dbXrefs | Ensembl:ENSG00000179344 MIM:604305; AllianceGenome:HGNC:4944 |
| Map Location | 6p21.32 |
| Variation Type | polymorphisms |
| refSNP ID | DQB1*0602 |
Sample information of multiple sclerosis:
| Detected Sample | blood |
| Sample Detail | peripheral blood lymphocytes |
| Detected Method | PCR |
| Disease | MS |
| Disease subtype | N/A |
| Population | Hong Kong |
| Sample Size | eleven Hong Kong MS patients and 36 healthy controls |
Literature information of multiple sclerosis :
| Pubmed ID | 1567812 |
| Year | 1992 |
| Title | Novel HLA-DR2-related haplotypes in Hong Kong Chinese implicate the DQB1*0602 allele in susceptibility to multiple sclerosis |
Results of multiple sclerosis :
| Risk Type | Disease risk |
| Main Result | Positive |
| Result | Novel DR,DQ linkage disequilibrium relationship in Hong Kong Chinese have permitted recognition of DQB1*0602 as a susceptibility allele in DRZpositive MS patients, although a role for the DRBl*1501 allele in MS pathogenesis has not been excluded by this study. |
| Mechanism/Pathway | N/A |
