Details

Home Details


Basic information of TNF :

Official Symbol of Gene TNF
Species Homo sapiens
Entrez Gene ID 7124
Official Full Name tumor necrosis factor
Also known as DIF; TNFA; TNFSF2; TNLG1F; TNF-alpha
Gene Type protein coding
dbXrefs Ensembl:ENSG00000232810 MIM:191160; AllianceGenome:HGNC:11892
Map Location 6p21.33
Variation Type genotype
refSNP ID (-238TNF*B1, -308TNF*A2,CTLA4*G)

Sample information of multiple sclerosis:

Detected Sample N/A
Sample Detail N/A
Detected Method N/A
Disease MS
Disease subtype N/A
Population Russian
Sample Size N/A

Literature information of multiple sclerosis :

Pubmed ID 19894308
Year 2009
Title [Genetic predisposition to multiple sclerosis as a polygenic autoimmune disease]

Results of multiple sclerosis :

Risk Type Disease risk
Main Result Positive
Result We also identified previously unknown MS-associated tri-allelic combinations: (-509 TGFb1*C, DRB1*18(3),CTLA4*G) and (-238TNF*B1, -308TNF*A2,CTLA4*G).
Mechanism/Pathway N/A