Basic information of TNF :
| Official Symbol of Gene | TNF |
| Species | Homo sapiens |
| Entrez Gene ID | 7124 |
| Official Full Name | tumor necrosis factor |
| Also known as | DIF; TNFA; TNFSF2; TNLG1F; TNF-alpha |
| Gene Type | protein coding |
| dbXrefs | Ensembl:ENSG00000232810 MIM:191160; AllianceGenome:HGNC:11892 |
| Map Location | 6p21.33 |
| Variation Type | allel |
| refSNP ID | rs1799964/C |
Sample information of multiple sclerosis:
| Detected Sample | blood |
| Sample Detail | N/A |
| Detected Method | N/A |
| Disease | MS |
| Disease subtype | N/A |
| Population | US |
| Sample Size | 276 cases and 590 controls |
Literature information of multiple sclerosis :
| Pubmed ID | 25137520 |
| Year | 2016 |
| Title | Heavy metals, organic solvents, and multiple sclerosis: An exploratory look at gene-environment interactions |
Results of multiple sclerosis :
| Risk Type | Phenotypic risk |
| Main Result | Positive |
| Result | For lead, there were six statistically significant environmental interactions identified: rs1799964/C (TNF-α), rs769178/T (TNF-β), rs2189480/T (VDR), rs3782905/C (VDR), rs4890785/T (MBP), and rs7412/T (APOE). |
| Mechanism/Pathway | N/A |
