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Basic information of IFNA17 :

Official Symbol of Gene IFNA17
Species Homo sapiens
Entrez Gene ID 3451
Official Full Name interferon alpha 17
Also known as IFNA; INFA; LEIF2C1; IFN-alphaI
Gene Type protein coding
dbXrefs Ensembl:ENSG00000234829 MIM:147583; AllianceGenome:HGNC:5422
Map Location 9p21.3
Variation Type polymorphism
refSNP ID N/A

Sample information of multiple sclerosis:

Detected Sample blood
Sample Detail N/A
Detected Method PCR
Disease MS
Disease subtype PPMS
Population the Northern Sweden Health and Disease Study (NSHDS) Cohort
Sample Size 399 MS cases;Referents (n=698)

Literature information of multiple sclerosis :

Pubmed ID 17956450
Year 2007
Title No support for a truncated interferon-alpha 17 allele as risk factor for MS

Results of multiple sclerosis :

Risk Type disease risk
Main Result Negative
Result Thus, our study does not support an association between the IFNA17 allele and risk for MS.
Mechanism/Pathway The finding, based on eight PPMS cases being positive for the allele whilst none of the referents were, may therefore be a post hoc type 1 error.