Details

Home Details


Basic information of TNF :

Official Symbol of Gene TNF
Species Homo sapiens
Entrez Gene ID 7124
Official Full Name tumor necrosis factor
Also known as DIF; TNFA; TNFSF2; TNLG1F; TNF-alpha
Gene Type protein coding
dbXrefs Ensembl:ENSG00000232810 MIM:191160; AllianceGenome:HGNC:11892
Map Location 6p21.33
Variation Type polymorphisms
refSNP ID Chr 6p21

Sample information of multiple sclerosis:

Detected Sample venous blood
Sample Detail N/A
Detected Method PCR
Disease MS
Disease subtype N/A
Population Northern Irish population
Sample Size N/A

Literature information of multiple sclerosis :

Pubmed ID 19244395
Year 2009
Title An investigation of susceptibility loci in benign, aggressive and primary progressive multiple sclerosis in Northern Irish population

Results of multiple sclerosis :

Risk Type Disease risk
Main Result Positive
Result Two microsatellite markers were significant: D3S1278 (Chr 3q13, P < 0.001) and tumor necrosis factor (TNF)-α (Chr 6p21, P < 0.001).
Mechanism/Pathway N/A