Basic information of ERVW-1 :

Official Symbol of Gene	ERVW-1
Species	Homo sapiens
Entrez Gene ID	30816
Official Full Name	endogenous retrovirus group W member 1, envelope
Also known as	ENV; ENVW; HERVW; ERVWE1; HERV7Q; HERV-7q; HERVWENV; HERV-W-ENV
Gene Type	protein coding
dbXrefs	Ensembl:ENSG00000242950 MIM:604659; AllianceGenome:HGNC:13525
Map Location	7q21.2
Variation Type	CNV
refSNP ID	MSRV

Sample information of multiple sclerosis:

Detected Sample	peripheral blood
Sample Detail	mononuclear cells
Detected Method	N/A
Disease	MS
Disease subtype	N/A
Population	Caucasian, with European ancestors
Sample Size	178 MS patients (62.9% women) and 124 controls (56.5% women)

Literature information of multiple sclerosis :

Pubmed ID	23308264
Year	2013
Title	The DNA copy number of human endogenous retrovirus-W (MSRV-type) is increased in multiple sclerosis patients and is influenced by gender and disease severity

Results of multiple sclerosis :

Risk Type	Phenotypic risk
Main Result	Positive
Result	MSRV increases its copy number in PBMC of MS patients and particularly in women with high clinical scores.
Mechanism/Pathway	N/A