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Basic information of HLA-DRB1 :

Official Symbol of Gene HLA-DRB1
Species Homo sapiens
Entrez Gene ID 3123
Official Full Name major histocompatibility complex, class II, DR beta 1
Also known as SS1; DRB1; HLA-DRB; HLA-DR1B
Gene Type protein coding
dbXrefs Ensembl:ENSG00000196126 MIM:142857; AllianceGenome:HGNC:4948
Map Location 6p21.32
Variation Type polymorphisms
refSNP ID DRB1*08

Sample information of multiple sclerosis:

Detected Sample N/A
Sample Detail N/A
Detected Method PCR
Disease MS
Disease subtype N/A
Population Canadian and European descent
Sample Size 1690 individuals from 350 affected sibling pair (ASP) families and 960 individuals from 187 AUNN families

Literature information of multiple sclerosis :

Pubmed ID 19098025
Year 2009
Title Epigenetics in multiple sclerosis susceptibility: difference in transgenerational risk localizes to the major histocompatibility complex

Results of multiple sclerosis :

Risk Type Disease risk
Main Result Negative
Result A comparison of the transmission of HLA-DRB1 alleles in ASP and AUNN families
Mechanism/Pathway N/A