Basic information of HLA-DRB1 :

Official Symbol of Gene	HLA-DRB1
Species	Homo sapiens
Entrez Gene ID	3123
Official Full Name	major histocompatibility complex, class II, DR beta 1
Also known as	SS1; DRB1; HLA-DRB; HLA-DR1B
Gene Type	protein coding
dbXrefs	Ensembl:ENSG00000196126 MIM:142857; AllianceGenome:HGNC:4948
Map Location	6p21.32
Variation Type	polymorphisms
refSNP ID	DRB1*15

Sample information of multiple sclerosis:

Detected Sample	N/A
Sample Detail	N/A
Detected Method	PCR
Disease	MS
Disease subtype	N/A
Population	Canadian and European descent
Sample Size	1690 individuals from 350 affected sibling pair (ASP) families and 960 individuals from 187 AUNN families

Literature information of multiple sclerosis :

Pubmed ID	19098025
Year	2009
Title	Epigenetics in multiple sclerosis susceptibility: difference in transgenerational risk localizes to the major histocompatibility complex

Results of multiple sclerosis :

Risk Type	Disease risk
Main Result	Positive
Result	The risk carried by HLA-DRB115 was increased in families with affected second-degree relatives (AUNN: OR 5 4.07) when compared with those consisting only first-degree relatives (ASP: OR 5 2.17), establishing heterogeneity of risk among HLADRB115 haplotypes based on whether collateral parental relatives are affected.
Mechanism/Pathway	N/A