Basic information of HLA-DRB1 :

Official Symbol of Gene	HLA-DRB1
Species	Homo sapiens
Entrez Gene ID	3123
Official Full Name	major histocompatibility complex, class II, DR beta 1
Also known as	SS1; DRB1; HLA-DRB; HLA-DR1B
Gene Type	protein coding
dbXrefs	Ensembl:ENSG00000196126 MIM:142857; AllianceGenome:HGNC:4948
Map Location	6p21.32
Variation Type	polymorphisms
refSNP ID	DRB1*1501

Sample information of multiple sclerosis:

Detected Sample	venous blood
Sample Detail	N/A
Detected Method	N/A
Disease	MS
Disease subtype	N/A
Population	Caucasian
Sample Size	70 Caucasian patients

Literature information of multiple sclerosis :

Pubmed ID	8244781
Year	1993
Title	The influence of HLA-DR and -DQ alleles on progression to multiple sclerosis following a clinically isolated syndrome

Results of multiple sclerosis :

Risk Type	Disease risk
Main Result	Positive
Result	Conversion to MS was positively associated with the DRB1*1501.DQA1*0102.DQBl*0602 haplotype, but the influence of HLA was only significant in patients with disseminated brain lesions at presentation (MRI positive); MS developed in 86% of MRI-positive, DRBl*1501-positive patients compared with 55% of MRI -positive, DRB 1 * 1501-negative patients.
Mechanism/Pathway	N/A