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Basic information of SELP :

Official Symbol of Gene SELP
Species Homo sapiens
Entrez Gene ID 6403
Official Full Name selectin P
Also known as CD62; GRMP; PSEL; CD62P; GMP140; LECAM3; PADGEM
Gene Type protein coding
dbXrefs Ensembl:ENSG00000174175 MIM:173610; AllianceGenome:HGNC:10721
Map Location 1q24.2
Variation Type SNP
refSNP ID rs6133

Sample information of multiple sclerosis:

Detected Sample N/A
Sample Detail N/A
Detected Method N/A
Disease MS
Disease subtype N/A
Population Italian and American
Sample Size Italian (169 MS, 149 healthy),American (122 MS, 50 healthy)

Literature information of multiple sclerosis :

Pubmed ID 19240957
Year 2009
Title Candidate gene analysis of selectin cluster in patients with multiple sclerosis

Results of multiple sclerosis :

Risk Type Disease risk
Main Result Negative
Result No significant differences in either allelic or genotypic frequency in all the SNPs tested were found in the Italian population. A tendency to an increased frequency of the rs6133 T allele was observed in the American population, but applying the Bonferroni correction the significance threshold was not reached.
Mechanism/Pathway the selectin gene cluster studied likely does not influence the susceptibility to MS in Caucasians.