Details

Home Details


Basic information of SELE :

Official Symbol of Gene SELE
Species Homo sapiens
Entrez Gene ID 6401
Official Full Name selectin E
Also known as ELAM; ESEL; CD62E; ELAM1; LECAM2; selectin-e
Gene Type protein coding
dbXrefs Ensembl:ENSG00000007908 MIM:131210; AllianceGenome:HGNC:10718
Map Location 1q24.2
Variation Type SNP
refSNP ID rs5368

Sample information of multiple sclerosis:

Detected Sample N/A
Sample Detail N/A
Detected Method N/A
Disease MS
Disease subtype N/A
Population Italian and American
Sample Size Italian (169 MS, 149 healthy),American (122 MS, 50 healthy)

Literature information of multiple sclerosis :

Pubmed ID 19240957
Year 2009
Title Candidate gene analysis of selectin cluster in patients with multiple sclerosis

Results of multiple sclerosis :

Risk Type Disease risk
Main Result Negative
Result Combining the two SNPs, we found no difference in haplotype distribution in patients compared with controls, either in Italian or in American population.
Mechanism/Pathway the selectin gene cluster studied likely does not influence the susceptibility to MS in Caucasians.