Basic information of IL-12B :
| Official Symbol of Gene | IL-12B |
| Species | Homo sapiens |
| Entrez Gene ID | 3593 |
| Official Full Name | interleukin 12B |
| Also known as | CLMF; NKSF; CLMF2; IMD28; IMD29; NKSF2; IL-12B |
| Gene Type | protein coding |
| dbXrefs | Ensembl:ENSG00000113302 MIM:161561; AllianceGenome:HGNC:5970 |
| Map Location | 5q33.3 |
| Variation Type | SNP |
| refSNP ID | rs3212227 |
Sample information of multiple sclerosis:
| Detected Sample | blood |
| Sample Detail | peripheral blood leukocytes |
| Detected Method | PCR-RFLP |
| Disease | MS |
| Disease subtype | N/A |
| Population | Chinese Southern Population |
| Sample Size | 178 MS patients and 221 health controls |
Literature information of multiple sclerosis :
| Pubmed ID | 24547735 |
| Year | 2014 |
| Title | Association of IL-23 and its receptor gene single-nucleotide polymorphisms with multiple sclerosis in Chinese southern population |
Results of multiple sclerosis :
| Risk Type | Disease risk |
| Main Result | Negative |
| Result | Our study showed that the IL-12B and IL23R gene SNPs does not seem to be associated with MS susceptibility in Chinese southern population. |
| Mechanism/Pathway | N/A |
