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Basic information of HLA-DPB1 :

Official Symbol of Gene HLA-DPB1
Species Homo sapiens
Entrez Gene ID 3115
Official Full Name major histocompatibility complex, class II, DP beta 1
Also known as DPB1; HLA-DP; HLA-DPB; HLA-DP1B
Gene Type protein coding
dbXrefs Ensembl:ENSG00000223865 MIM:142858; AllianceGenome:HGNC:4940
Map Location 6p21.32
Variation Type polymorphisms
refSNP ID DPB10501

Sample information of multiple sclerosis:

Detected Sample blood
Sample Detail peripheral blood lymphocytes
Detected Method PCR
Disease MS
Disease subtype RRMS,SPMS
Population Japanese
Sample Size 10 NMO and 15 MS, and 36 healthy subjects

Literature information of multiple sclerosis :

Pubmed ID 17125797
Year 2007
Title Interferon beta-1b exacerbates multiple sclerosis with severe optic nerve and spinal cord demyelination

Results of multiple sclerosis :

Risk Type Phenotypic risk
Main Result Positive
Result MS with DPB10501 showed severe optic neuritis, myelitis and CSF pleocytosis
Mechanism/Pathway N/A