Basic information of Tcrb :

Official Symbol of Gene	Tcrb
Species	Mus musculus
Entrez Gene ID	21577
Official Full Name	T cell receptor beta chain
Also known as	Tib; TCRbeta
Gene Type	protein coding
dbXrefs	N/A
Map Location	6 B1; 6
Variation Type	SNP
refSNP ID	Vβ8

Sample information of multiple sclerosis:

Detected Sample	N/A
Sample Detail	N/A
Detected Method	Southern blot
Disease	EAE
Disease subtype	N/A
Population	PL/J mice,(PLSJ)F1 mouse
Sample Size	14 individual homozygous PL/J mice, a single (PLSJ)F1 mouse

Literature information of multiple sclerosis :

Pubmed ID	2452856
Year	1988
Title	Predominant expression of a T cell receptor V beta gene subfamily in autoimmune encephalomyelitis

Results of multiple sclerosis :

Risk Type	disease risk
Main Result	Positive
Result	Our results demonstrate that an mAb specific for the TCR Vβ8 subfamily is effective in preventing autoimmune encephalomyelitis .
Mechanism/Pathway	Our findings indicate that there is restricted TCRVβ usage in the autoimmune Tcell response to the dominant encephalitogenic NH2-terminal epitope of the MBP.