Basic information of PTPN22 :
| Official Symbol of Gene | PTPN22 |
| Species | Homo sapiens |
| Entrez Gene ID | 26191 |
| Official Full Name | protein tyrosine phosphatase non-receptor type 22 |
| Also known as | LYP; PEP; LYP1; LYP2; PTPN8; PTPN22.5; PTPN22.6 |
| Gene Type | protein coding |
| dbXrefs | Ensembl:ENSG00000134242 MIM:600716; AllianceGenome:HGNC:9652 |
| Map Location | 1p13.2 |
| Variation Type | polymorphisms |
| refSNP ID | 620W |
Sample information of multiple sclerosis:
| Detected Sample | N/A |
| Sample Detail | N/A |
| Detected Method | N/A |
| Disease | MS |
| Disease subtype | N/A |
| Population | UK |
| Sample Size | 456 MS patients(249 subjects with CD and their 207 matched control subjects) |
Literature information of multiple sclerosis :
| Pubmed ID | 16391555 |
| Year | 2006 |
| Title | Evaluating the role of the 620W allele of protein tyrosine phosphatase PTPN22 in Crohn’s disease and multiple sclerosis |
Results of multiple sclerosis :
| Risk Type | Phenotypic risk |
| Main Result | Negative |
| Result | these analyses do not exclude a role for the PTPN22 allele in susceptibility to CD or MS. |
| Mechanism/Pathway | N/A |
