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Basic information of TRB :

Official Symbol of Gene TRB
Species Homo sapiens
Entrez Gene ID 6957
Official Full Name T cell receptor beta locus
Also known as TCRB; TRB@
Gene Type protein coding
dbXrefs AllianceGenome:HGNC:12155
Map Location 7q34
Variation Type Haplotype assignments
refSNP ID N/A

Sample information of multiple sclerosis:

Detected Sample N/A
Sample Detail peripheral blood or lymphoblastoid B cell lines
Detected Method N/A
Disease MS
Disease subtype N/A
Population Caucasian
Sample Size 38 unrelated Caucasian patients,control population consisted of the healthy, unrelated, Caucasian parents or grandparents

Literature information of multiple sclerosis :

Pubmed ID 1674514
Year 1991
Title Further localization of a multiple sclerosis susceptibility gene on chromosome 7q using a new T cell receptor beta-chain DNA polymorphism

Results of multiple sclerosis :

Risk Type disease risk
Main Result Positive
Result The reported MS association with the TCR-β gene complex therefore does not appear to be due to genes within the diversity, joining, or constant region but more likely involves a specific gene(s) within the variable region.
Mechanism/Pathway N/A