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Basic information of SCN10A :

Official Symbol of Gene SCN10A
Species Homo sapiens
Entrez Gene ID 6336
Official Full Name sodium voltage-gated channel alpha subunit 10
Also known as PN3; SNS; FEPS2; Nav1.8
Gene Type protein coding
dbXrefs Ensembl:ENSG00000185313 MIM:604427; AllianceGenome:HGNC:10582
Map Location 3p22.2
Variation Type SNP
refSNP ID rs6801957

Sample information of multiple sclerosis:

Detected Sample N/A
Sample Detail N/A
Detected Method N/A
Disease MS
Disease subtype N/A
Population N/A
Sample Size 161 patients with relapsing-onset MS and 94 demographically comparable healthy participants

Literature information of multiple sclerosis :

Pubmed ID 26740675
Year 2016
Title Channelopathy-related SCN10A gene variants predict cerebellar dysfunction in multiple sclerosis

Results of multiple sclerosis :

Risk Type Phenotypic risk
Main Result Positive
Result Two SCN10A polymorphisms in high linkage disequilibrium showed significant association with MSFC performance in patients with MS.
Mechanism/Pathway N/A