Basic information of HLA-A :
| Official Symbol of Gene | HLA-A |
| Species | Homo sapiens |
| Entrez Gene ID | 3105 |
| Official Full Name | major histocompatibility complex, class I, A |
| Also known as | HLAA |
| Gene Type | protein coding |
| dbXrefs | Ensembl:ENSG00000206503 MIM:142800; AllianceGenome:HGNC:4931 |
| Map Location | 6p22.1 |
| Variation Type | polymorphisms |
| refSNP ID | HLA-A*31:01 |
Sample information of multiple sclerosis:
| Detected Sample | N/A |
| Sample Detail | N/A |
| Detected Method | N/A |
| Disease | MS |
| Disease subtype | N/A |
| Population | N/A |
| Sample Size | N/A |
Literature information of multiple sclerosis :
| Pubmed ID | 32242486 |
| Year | 2021 |
| Title | In silico study of the association of the HLA-Aβ31:01 allele (human leucocyte antigen allele 31:01) with neuroantigenic epitopes of PLP (proteolipid protein), MBP (myelin basic protein) and MOG proteins (myelin oligodendrocyte glycoprotein) for studying the multiple sclerosis disease pathogenesis |
Results of multiple sclerosis :
| Risk Type | Disease risk |
| Main Result | Positive |
| Result | Further investigations of this peptide revealed that the binding of C-terminal residue of this peptide has a more significant effect on binding to this allele than the N-terminal part of the peptide. |
| Mechanism/Pathway | N/A |
