Basic information of HLA-DRB1 :
| Official Symbol of Gene | HLA-DRB1 |
| Species | Homo sapiens |
| Entrez Gene ID | 3123 |
| Official Full Name | major histocompatibility complex, class II, DR beta 1 |
| Also known as | SS1; DRB1; HLA-DRB; HLA-DR1B |
| Gene Type | protein coding |
| dbXrefs | Ensembl:ENSG00000196126 MIM:142857; AllianceGenome:HGNC:4948 |
| Map Location | 6p21.32 |
| Variation Type | polymorphisms |
| refSNP ID | DRB1*12:01 |
Sample information of multiple sclerosis:
| Detected Sample | N/A |
| Sample Detail | DNA samples |
| Detected Method | PCR |
| Disease | MS |
| Disease subtype | N/A |
| Population | African Americans |
| Sample Size | 3,254 African Americans (1,162 cases and 2,092 controls) |
Literature information of multiple sclerosis :
| Pubmed ID | 23771490 |
| Year | 2013 |
| Title | Genetic risk variants in African Americans with multiple sclerosis |
Results of multiple sclerosis :
| Risk Type | Disease risk |
| Main Result | Negative |
| Result | The following major histocompatibility complex risk alleles were replicated: HLADRB1*15:01, HLA-DRB1*03:01, as well as HLA-DRB1*04:05 and the African-specific risk allele of HLA-DRB1*15:03. |
| Mechanism/Pathway | N/A |
