Basic information of IRF8 :
| Official Symbol of Gene | IRF8 |
| Species | Homo sapiens |
| Entrez Gene ID | 3394 |
| Official Full Name | interferon regulatory factor 8 |
| Also known as | ICSBP; IRF-8; ICSBP1; IMD32A; IMD32B; H-ICSBP |
| Gene Type | protein coding |
| dbXrefs | Ensembl:ENSG00000140968 MIM:601565; AllianceGenome:HGNC:5358 |
| Map Location | 16q24.1 |
| Variation Type | SNP |
| refSNP ID | rs17445836 |
Sample information of multiple sclerosis:
| Detected Sample | blood |
| Sample Detail | N/A |
| Detected Method | Real-Time PCR |
| Disease | MS |
| Disease subtype | PPMS, RRMS, SPMS, PRMS |
| Population | Spain |
| Sample Size | 2515 MS patients and 2942 healthy controls |
Literature information of multiple sclerosis :
| Pubmed ID | 20430450 |
| Year | 2010 |
| Title | Validation of the CD6 and TNFRSF1A loci as risk factors for multiple sclerosis in Spain |
Results of multiple sclerosis :
| Risk Type | Disease risk |
| Main Result | Positive |
| Result | IRF8 could not be established beyond doubt as risk locus for MS due to the exclusion of the Bilbao and Madrid datasets. |
| Mechanism/Pathway | N/A |
