Basic information of CD86 :
| Official Symbol of Gene | CD86 |
| Species | Homo sapiens |
| Entrez Gene ID | 942 |
| Official Full Name | CD86 molecule |
| Also known as | B70; B7-2; B7.2; LAB72; CD28LG2 |
| Gene Type | protein coding |
| dbXrefs | Ensembl:ENSG00000114013 MIM:601020; AllianceGenome:HGNC:1705 |
| Map Location | 3q13.33 |
| Variation Type | SNP |
| refSNP ID | rs9282641*G |
Sample information of multiple sclerosis:
| Detected Sample | blood |
| Sample Detail | B cells |
| Detected Method | PCR |
| Disease | MS |
| Disease subtype | N/A |
| Population | Caucasian descent(case) and Cambridge BioResource(control) |
| Sample Size | 68 patients and 162 healthy controls |
Literature information of multiple sclerosis :
| Pubmed ID | 29361022 |
| Year | 2018 |
| Title | Multiple sclerosis risk variants alter expression of co-stimulatory genes in B cells |
Results of multiple sclerosis :
| Risk Type | Disease risk |
| Main Result | Positive |
| Result | We found that carrying the risk allele rs4810485*T lowered the cell-surface expression of CD40 in all tested B cell subtypes, while carrying the risk allele rs9282641*G increased the expression of CD86. |
| Mechanism/Pathway | N/A |
