Basic information of PRNP :
| Official Symbol of Gene | PRNP |
| Species | Homo sapiens |
| Entrez Gene ID | 5621 |
| Official Full Name | prion protein |
| Also known as | CJD; GSS; PrP; ASCR; KURU; PRIP; PrPc; CD230; AltPrP; p27-30; PrP27-30; PrP33-35C |
| Gene Type | protein coding |
| dbXrefs | Ensembl:ENSG00000171867 MIM:176640; AllianceGenome:HGNC:9449 |
| Map Location | 20p13 |
| Variation Type | SNP |
| refSNP ID | Prnp129 M/V |
Sample information of multiple sclerosis:
| Detected Sample | N/A |
| Sample Detail | N/A |
| Detected Method | N/A |
| Disease | MS |
| Disease subtype | PPMS |
| Population | N/A |
| Sample Size | 498 patients with PPMS and 600 healthy controls |
Literature information of multiple sclerosis :
| Pubmed ID | 21320996 |
| Year | 2011 |
| Title | No association between genetic polymorphism at codon 129 of the prion protein gene and primary progressive multiple sclerosis |
Results of multiple sclerosis :
| Risk Type | Disease risk |
| Main Result | Negative |
| Result | There was no statistically significant difference in frequency of Prnp129 genotypes between patients with PPMS and controls (P =.14) |
| Mechanism/Pathway | N/A |
